Aluminum Acetate Solution: Topical

What is aluminum acetate solution, topical?

Aluminum acetate solution, topical (Burow’s solution) is an astringent and drying agent used for the temporary relief of minor skin irritation such as insect bites, rashes, and allergies. It cleanses, cools, and dries inflamed skin. Burow’s solution is also used to treat ear infections (otitis externa) due to its antibacterial effects, often in combination with hydrocortisone. It is used in dogs and cats.

There is no veterinary brand of aluminum acetate solution, topical. Burow’s solution is available as an over-the-counter human product but should always be used under the supervision and guidance of a veterinarian. It is commonly available through veterinary compounding companies and is prescribed off label to treat inflammatory skin conditions. 

It is used “off label” or “extra label” in animals. Many drugs are commonly prescribed for off-label use in veterinary medicine. “Off label” means the drug is being used in a way that has not been reviewed or approved by the the U.S. Food and Drug Administration (FDA) or Health Canada. In these instances, follow your veterinarian’s directions and cautions carefully, as they may be significantly different from those on the label. 

How do I give my pet aluminum acetate solution, topical?

Aluminum acetate solution, topical, comes in a topical liquid form. 

• This medication should only be used topically.
• Topical use on the skin is usually by way of a wet compress, dressing or soak.
• Topical use in the ear is usually by way of liquid drops.
• Follow your veterinarian’s directions and measure liquid forms of this medication carefully.
• Avoid contact with the eyes.
• Wash your hands after application.
• Do not cover the application site with plastic or airtight dressing; allow for drying and evaporation. 

This medication will take effect quickly, in about one to two hours, but its effects may not be noticeable for a few days. 

What if I miss giving my pet the medication?

If you miss a dose of aluminum acetate solution, topical, give it as soon as you remember and then continue with the regular dosing schedule. However, if it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not give the pet two doses at once. 

Are there any potential side effects from aluminum acetate solution, topical?

Aluminum acetate solution, topical, may cause the following side effects:

• dry skin or skin irritation in some patients
• redness of skin

If excessive skin irritation occurs or the existing skin irritation and/or swelling worsens, discontinue this medication, and contact your veterinarian immediately. 

The following reactions are rare, but if they occur, contact your veterinarian immediately:

• an allergic reaction such as irregular breathing, rash, fever, puffiness and swelling around the face

Drug sensitivities can develop over time with repeated exposure. Your pet may have no reaction after the first few doses but may develop a sensitivity later. It is important to watch for signs of an allergic reaction over the entire course of treatment.

This short-acting medication should stop working within 24 hours, although effects may last longer in pets with liver or kidney disease.

Are there any risk factors for this medication?

This medication should NOT BE USED in pets who have a known sensitivity to Burow’s solution or a previous allergic reaction to this medication.

Are there any drug interactions I should be aware of?

Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking before starting any new treatment. Aluminum acetate, topical, is not known to have any specific drug interactions.

Is any monitoring needed with this medication?

At home, monitor for any side effects such as those noted above. If side effects occur, discontinue the medication, and contact your veterinarian. 

How do I store aluminum acetate solution, topical?

• Store this medication at controlled room temperature, away from heat and direct sunlight. 
• Store this mediation in its original container. 
• Keep this medication out of reach of children and pets.
• Ask your veterinarian for disposal instructions. Do not flush medications down the sink or toilet unless instructed to do so. 

What should I do in case of emergency?

If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility.